Quality of life in down syndrome in Brazil

Background: Down syndrome (DS) is the most common identified genetic cause of developmental delay and intellectual disability. DS characterized by a regular trisomy 21 in 95% cases 5% form translocation and/or mosaicism (Malt et al., 2013). Because presence extra material from chromosome 21, children with have medical conditions, cognitive impairment, multiple malformations, such as congenital heart defect, present 50% patients. While there been scientific advances general health, few people an independent life, them live their parents, some work are married or post-secondary education. Their potential capacity not considered, nor effective therapeutic approaches used to develop fullest.